TRANSCRIPTOME ANALYSIS OF HOMO SAPIENS AND MUS MUSCULUS REVEALS MECHANISMS OF CD8+ T CELL EXHAUSTION CAUSED BY DIFFERENT FACTORS.

Transcriptome analysis of Homo sapiens and Mus musculus reveals mechanisms of CD8+ T cell exhaustion caused by different factors.

T cell exhaustion is a state of T cell dysfunction during chronic infection and cancer.Antibody-targeting immune checkpoint inhibitors to reverse T cell exhaustion is a promising approach for cancer Musculoskeletal Health immunotherapy.However, molecular mechanisms of T cell exhaustion remain incompletely understood.Here, we performed a transcripto

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